RUNX1T1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: runt-related transcription factor 1; translocated to, 1(cyclin D-related)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 70-75 kDa
Uniprot: Q06455
Gene id: 862
Background: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8
ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem
progenitor cell self-renewal(PubMed:23812588).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: RUNX1T1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: runt-related transcription factor 1; translocated to, 1(cyclin D-related)
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 70-75 kDa
Uniprot: Q06455
Gene id: 862
Background: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8
ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem
progenitor cell self-renewal(PubMed:23812588).
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: RUNX1T1
Purification: Immunogen affinity purified
Reactivity: Human, Mouse